The exact causes of fusarium keratitis are not known, but there are certain risk factors which exist. These risk factors include trauma resulting in plant material entering the eye, chronic eye disease and a compromised immune system. Contact lens use has also been linked to fusarium keratitis although it is not believed that contact lenses directly cause the infection. In most cases, misuse of the contact lenses and poor hygiene contribute to the risk for fusarium keratitis.

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